Gene Mb0784c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameadhB
Gene length1128 bp
IdentifierMb0784c
Location 856888 bp
Protein summary information
Molecular mass39747.7 Da
Isoelectric point4.9263
Protein length375 amino acids
Cross-references
UniProtQ7U1B9
UniProtKB/TrEMBLX2BG32, Q7U1B9
General annotation
TypeCDS
FunctionUnknown
Productpossible zinc-containing alcohol dehydrogenase nad dependent adhb
CommentsMb0784c, adhB, len: 375 aa. Equivalent to Rv0761c,len: 375 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 375 aa overlap). Possible adhB,zinc-containing alcohol dehydrogenase NAD-dependant (EC 1.1.1.1), similar to others e.g. AAC15839.1|AF060871_4 hypothetical alcohol dehydrogenase from Rhodococcus rhodochrous (370 aa), FASTA scores: opt: 1234, E(): 0,(46.8% identity in 370 aa overlap); P80468|ADH2_STRCA ALCOHOL DEHYDROGENASE II from Struthio camelus (Ostrich) (379 aa); Q03505|ADH1_RABIT alcohol dehydrogenase alpha chain from Oryctolagus cuniculus (Rabbit) (374 aa), FASTA scores: opt: 872, E(): 0, (39.1% identity in 379 aa overlap); etc. Also similar to adhD alcohol dehydrogenase from Mycobacterium tuberculosis (368 aa). Contains PS00059 Zinc-containing alcohol dehydrogenases signature. BELONGS TO THE ZINC-CONTAINING ALCOHOL DEHYDROGENASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS856888858015-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0784c|adhB
MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCRSDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPSCGKCPSCQAGMRNLCDLGAGLLAGESVTDGSFRIQARGQNVYPMTLLGTFSPYMVVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDVAIVGLGGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDINAALMGIAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIGSLVDTQVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLDDMVTTAYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
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