Gene Mb0819c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE OXIDOREDUCTASE [FIRST PART] |
| Comments | Mb0819c, -, len: 299 aa. Equivalent to 5' end of Rv0794c, len: 499 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 263 aa overlap). Probable oxidoreductase (EC 1.-.-.-), possibly dihydrolipoamide dehydrogenase (EC 1.8.1.4) or mercuric reductase (EC 1.16.1.1). Highly similar to CAB62675.1|AL133422 probable oxidoreductase from Streptomyces coelicolor (477 aa); and similar to various oxidoreductases e.g. P08663|MERA_STAAU MERCURIC REDUCTASE (HG(II) REDUCTASE) (EC 1.16.1.1) from Staphylococcus aureus (547 aa); AAK70920.1|AC087551_19|AC087551 putative lipoamide dehydrogenase from Oryza sativa (563 aa); NP_437349.1|NC_003078 putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase, similar to mercuric reductases protein from Sinorhizobium meliloti (473 aa); Q04829|DLDH_HALVO DIHYDROLIPOAMIDE DEHYDROGENASE (EC 1.8.1.4) from Haloferax volcanii (475 aa); P08332|MERA_SHIFL MERCURIC REDUCTASE (EC 1.16.1.1) (564 aa), FASTA scores: opt: 522, E(): 3.7e-26, (31.7% identity in 467 aa overlap); P72740|DLDH_SYNY3|Q53395|LPDA|PDHD|SLR1096 DIHYDROLIPOAMIDE DEHYDROGENASE (EC 1.8.1.4) from Synechocystis sp. strain PCC 6803 (474 aa), FASTA scores: opt: 602, E(): 2.3e-31, (31.0% identity in 493 aa overlap); etc. Note that previously known as lpdB. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv0794c exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base deletion (a-*) splits Mb0818c into 2 parts, Mb0818a and Mb0818b. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 889926 | 890825 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0819c|Mb0819c
MTAAQQDQAPMATPGCREGETYDVVVLGAGPVGQNVADRARAGGLRVAVVERELVGGECSYWACVPSKALLRPVIAISDARRVDGAREAVDGSINTAGVFGRRNRYVAHWDDTGQADWVSGIGATLIRGDGRLDGPRRVVVTKSSGESVALTARHAVVICTGSRPALPDLPGITEARPWTNRQATDNSTVPDRLAIVGAGGVGVEMATAWQGLGASVTLLARGSGLLPRMEPFVGELIGRGLADAGVDVRVGVSVRALGRPNPLAQWSSSWTTVPSCGSTRYSSPPAEHREPTTSAWRQ
Bibliography
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