Gene Mb0874c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0874c
Gene length828 bp
IdentifierMb0874c
Location 948396 bp
Protein summary information
Molecular mass29267.1 Da
Isoelectric point5.5328
Protein length275 amino acids
Orthologs
M. tuberculosis H37RvRv0851c
M. tuberculosis MTBC0mtbc0_000906
Cross-references
UniProtA0A1R3XXK9
InterProIPR002198, IPR002347, IPR016040, IPR020904
UniProtKB/TrEMBLQ7U142
General annotation
TypeCDS
FunctionUnknown
Productprobable short-chain type dehydrogenase/reductase
CommentsMb0874c, -, len: 275 aa. Equivalent to Rv0851c,len: 275 aa, from Mycobacterium tuberculosis strain H37Rv,(99.3% identity in 275 aa overlap). Probable short-chain dehydrogenase/reductase (EC 1.-.-.-), similar to many e.g. Q01198|LIGD_PSEPA C ALPHA-DEHYDROGENASE (EC 1.1.1.-)(SDR FAMILY) from Pseudomonas paucimobilis (Sphingomonas paucimobilis) (305 aa); D11473|PSELIG_1 C alpha-dehydrogenase from P. paucimobilis (305 aa), FASTA scores: opt: 468, E(): 4.9e-23, (30.8% identity in 279 aa overlap); NP_421969.1|NC_002696 short chain dehydrogenase family protein from Caulobacter crescentus (278 aa); etc. Contains PS00061 Short-chain dehydrogenases/reductases family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS948396949223-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0874c|Mb0874c
MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHGVMCDVRHREEVTHLADEAFRLLGHFDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAKYGVVGLAETLAREVTADGIGVSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILANRLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH
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