Gene Mb0997c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadE12
Gene length1167 bp
IdentifierMb0997c
Location 1083023 bp
Protein summary information
Molecular mass41524.4 Da
Isoelectric point5.8542
Protein length388 amino acids
Orthologs
M. tuberculosis H37RvRv0972c
M. tuberculosis MTBC0mtbc0_001038
Cross-references
UniProtQ7U0Y2
UniProtKB/TrEMBLX2BGF7, Q7U0Y2
General annotation
TypeCDS
FunctionUnknown
Productacyl-coa dehydrogenase fade12
CommentsMb0997c, fadE12, len: 388 aa. Equivalent to Rv0972c, len: 388 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 388 aa overlap). Probable fadE12, acyl-CoA dehydrogenase (EC 1.3.99.-), highly similar to many e.g. CAB95893.1|AL359988 putative acyl CoA dehydrogenase from Streptomyces coelicolor (382 aa); P45857|ACDB_BACSU from Bacillus subtilis (379 aa), FASTA scores: opt: 576, E(): 2.3e-26, (29.7% identity in 381 aa overlap); etc.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10830231084189-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0997c|fadE12
MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTGKLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAHLFAGLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
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