Gene Mb1003c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS17
Gene length1008 bp
IdentifierMb1003c
Location 1093800 bp
Protein summary information
Molecular mass31380.6 Da
Isoelectric point4.7363
Protein length335 amino acids
Orthologs
M. tuberculosis H37RvRv0978c
Cross-references
UniProtA0A1R3XZ35
InterProIPR000084, IPR001258, IPR011964, IPR013017, IPR015943
UniProtKB/TrEMBLQ7U0X7
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs17
CommentsMb1003c, PE_PGRS17, len: 335 aa. Similar to Rv0978c, len: 331 aa, from Mycobacterium tuberculosis strain H37Rv, (93.7% identity in 335 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, highly similar to others e.g. Z95387|MTCY1A10_19 from Mycobacterium tuberculosis (461 aa), FASTA score: (73.6% identity in 277 aa overlap); etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 115 bp to 127 bp substitution leads to a slightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (335 aa versus 331 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10938001094807-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1003c|PE_PGRS17
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLVAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVLALSQAGSTYAVAEAASATPLQQIEQALLGVINTPTEALVGRKLIGDGAHGAPGTGQAGGAGGILWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITIGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS
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