Gene Mb1051 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeno
Gene length1290 bp
IdentifierMb1051
Location 1145011 bp
Protein summary information
Molecular mass44862.4 Da
Isoelectric point4.2261
Protein length429 amino acids
Orthologs
M. tuberculosis H37RvRv1023
M. tuberculosis MTBC0mtbc0_001099
Cross-references
UniProtQ7U0U6
UniProtKB/TrEMBLX2BGU2, Q7U0U6
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ENOLASE ENO
CommentsMb1051, eno, len: 429 aa. Equivalent to Rv1023,len: 429 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 429 aa overlap). Probable eno, enolase (EC 4.2.1.11), highly similar to others e.g. ENO_ECOLI|P08324 enolase from Escherichia coli (431 aa),FASTA scores: opt: 1487, E(): 0, (55.5% identity in 422 aa overlap); etc. MAGNESIUM IS REQUIRED FOR CATALYSIS AND FOR STABILIZING THE DIMER. BELONGS TO THE ENOLASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS11450111146300+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1051|eno
MPIIEQVGAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFACETK
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