Gene Mb1078 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1078
Gene length447 bp
IdentifierMb1078
Location 1172835 bp
Protein summary information
Molecular mass15980.3 Da
Isoelectric point10.5275
Protein length148 amino acids
Orthologues
M. tuberculosisRv1049
Cross-references
UniProtA0A1R3XX75
InterProIPR000835, IPR011991
UniProtKB/TrEMBLQ7U0S7
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REPRESSOR PROTEIN
CommentsMb1078, -, len: 148 aa. Equivalent to Rv1049, len: 148 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 148 aa overlap). Probable transcriptional repressor protein, similar to many e.g. P74870 NEGATIVE REGULATOR OF EMR LOCUS EMR from Salmonella typhimurium (149 aa), FASTA scores: opt: 146, E(): 0.0011,(31.6% identity in 95 aa overlap). Contains probable helix-turn -helix motif at aa 58-79 (Score 1495, +4.28 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS11728351173281+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1078|Mb1078
MGKGAAFDECACYTTRRAARQLGQAYDRALRPSGLTNTQFSTLAVISLSEGSAGIDLTMSELAARIGVERTTLTRNLEVMRRDGLVRVMAGADARCKRIELTAKGRAALQKAVPLWRGVQAEVTASVGDWPRVRRDIANLGQAAEACR
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