Gene Mb1111 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemca
Gene length867 bp
IdentifierMb1111
Location 1207880 bp
Protein summary information
Molecular mass32731.8 Da
Isoelectric point4.9277
Protein length288 amino acids
Orthologues
M. tuberculosisRv1082
Cross-references
UniProtA0A1R3XXA8
InterProIPR003737, IPR017811, IPR024078
UniProtKB/TrEMBLQ7VEZ7
General annotation
TypeCDS
FunctionUnknown
ProductMycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase)
CommentsMb1111, mca, len: 288 aa. Equivalent to Rv1082,len: 288 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 288 aa overlap). mca, mycothiol conjugate amidase (see citation below), equivalent to NP_302547.1|NC_002677 conserved hypothetical protein from Mycobacterium leprae (290 aa), FASTA scores: opt: 1737,E(): 0, (86.4% identity in 287 aa overlap); and similar to Q54358|X79146 lmbE protein from Streptomyces lincolnensis (270 aa). Also similar to Rv1170|MTV005.06|MSHB GlcNAc-Ins deacetylase from Mycobacterium tuberculosis (303 aa),FASTA scores: opt: 411, E(): 9.4e-20, (35.8% identity in 299 aa overlap).
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12078801208746+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1111|mca
MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNPAMDLPDVHGRIAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLPDDCFARVPLEVSTEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSVAAYEAAGDFCRFPDAGEPWTVSKLYYVHGFLRERMQMLQDEFARHGQRGPFEQWLAYWDPDHDFLTSRVTTRVECSKYFSQRDDALRAHATQIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP
Bibliography
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