Gene Mb1115 in Mycobacterium bovis AF2122/97
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1115
Gene length789 bp
IdentifierMb1115
Location 1211955 bp
Protein summary information
Molecular mass29479.4 Da
Isoelectric point5.6603
Protein length262 amino acids
Orthologs
M. tuberculosis H37RvRv1086
M. tuberculosis MTBC0mtbc0_001166
Cross-references
UniProtQ7U0P8
UniProtKB/TrEMBLX2BH82, Q7U0P8
General annotation
TypeCDS
FunctionUnknown
ProductSHORT (C15) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-FPP SYNTHASE) (Z-FARNESYL DIPHOSPHATE SYNTHASE) (Z-FPP SYNTHETASE) (Z-FARNESYL DIPHOSPHATE SYNTHETASE) (GERANYLTRANSTRANSFERASE) (FARNESYL PYROPHOSPHATE SYNTHETASE)
CommentsMb1115, -, len: 262 aa. Equivalent to Rv1086, len: 262 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 262 aa overlap). Short (C15) chain Z-isoprenyl diphosphate synthase (EC 2.5.1.10) (see citations below), equivalent to NP_302598.1|NC_002677 possible undecaprenyl pyrophosphate synthetase from Mycobacterium leprae (262 aa), similar to many hypothetical proteins and several potential members of the upp synthase family e.g. NP_296167.1|NC_001263 undecaprenyl diphosphate synthase from Deinococcus radiodurans (339 aa); P20182|YT14_STRFR Hypothetical protein from Streptomyces fradiae (259 aa), FASTA scores: opt: 840, E(): 0, (51.0% identity in 259 aa overlap); and P38118|YARF_CORGL Hypothetical protein from Corynebacterium glutamicicum (234 aa), FASTA scores: opt: 729, E(): 0, (56.0% identity in 209 aa overlap); etc. Also similar to Rv2361c|MTCY27.19 (296 aa) (35.6% identity in 233 aa overlap). Contains PS01066 Uncharacterized protein family UPF0015 signature. SEEMS TO BELONG TO THE UPP SYNTHETASE FAMILY.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12119551212743+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1115|Mb1115
MEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDGNRRWARSAGYDDVSYGYRMGAAKIAEMLRWCHEAGIELATVYLLSTENLQRDPDELAALIEIITDVVEEICAPANHWSVRTVGDLGLIGEEPARRLRGAVESTPEVASFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELVDAVTVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHWPAFRHVDFLRALRDYSARHRRYGR
Bibliography
No article yet recorded