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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs21
CommentsMb1116, PE_PGRS21, len: 774 aa. Similar to Rv1087,len: 767 aa, from Mycobacterium tuberculosis strain H37Rv,(96.8% identity in 783 aa overlap). Member of the M. tuberculosis PE family, PGRS subfamily of gly-rich proteins. Similar to Rv1090|AL021897|MTV017_43 Mycobacterium tuberculosis H37Rv (853 aa), FASTA scores: opt: 2819, E(): 0, (59.8% identity in 860 aa overlap). Contains PS00583 pfkB family of carbohydrate kinases signature 1 near C -terminus. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis,insertions of 3 bp (*-gcg) and 45 bp, and deletions of 18 bp and 9 bp (ggtggggcc-*), lead to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (774 aa versus 767 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12129201215244+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1116|PE_PGRS21
MSFVVVAPEVLAAAASDLAGIGSTLAQANAAALAPTTAVLAAGADEVSAAIASLFGAHGQAYQAVSAQMSAFHAQFMQALTGAGGAYAAAEAVNVSAAQSVEQDLLAAINARFERIFGRPLIGDGANGGPGQDGGPGGLLYGNGGNGGTSTTVGMAGGNGGAAGLIGNGGFGGGGGPGAAGGNGGAGGWLFGNGGAGGAGGLGVAPGVPGGAGGAGGAGGVGGPAGLWGHGGAGGAGGAGVAGAGGFEGTIGAGGAGGVGGAGGVGGAGGAGGWLYGDAGAGGDGGVGGAGGTGGLGNRGGAGGAGGAGGVGGAGGAAGLWGGGGAGGVGGTGGGAGLGAQSVTFSSSLSGLSGGDGGAGGAGGAGGAGGTGGWLYGGGGAAGSGGDGGTGGQGGAGGAGVFSLFGSGGGPGGNGGVGGVGGVGGAGGRAGLFGVGGLGGAGGDAGDSGEGGFGGPGLAGGLFGNPGNGGVGGIGGDAAAGGAGGAGGNGGWLFGNGGAGGSGGDGGAAGRGGAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGGTAGLFGDGGAGGAGAAGGFGGISAATPSAGSEGAMGGAGGVGGNARLLGTGGAGGVGGGGGAGGDGGRGGVATPGGQGGDAGDGGAGGAGGNGGGGASGAGGWLLGTGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGGGGGVGGNGATGPWLFGDGGAGGGGGAGGIGGDGGPTPGSTGAGAAGGHGGDAQLIGNGGHGGAGGTGVPNGSGGAGGLSGLLFGEPGANG
      
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