Gene Mb1122c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecoaA
Gene length939 bp
IdentifierMb1122c
Location 1220620 bp
Protein summary information
Molecular mass35656.9 Da
Isoelectric point7.894
Protein length312 amino acids
Orthologs
M. tuberculosis H37RvRv1092c
M. tuberculosis MTBC0mtbc0_001175
Cross-references
UniProtP63811
UniProtKB/TrEMBLX2BGW8, P63811
General annotation
TypeCDS
FunctionUnknown
ProductProbable pantothenate kinase coaA (Pantothenic acid kinase)
CommentsMb1122c, coaA, len: 312 aa. Equivalent to Rv1092c,len: 312 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 312 aa overlap). Probable coaA,pantothenate kinase (EC 2.7.1.33), similar to many e.g. P15044|COAA_ECOLI Escherichia coli (316 aa), FASTA scores :opt: 1079, E(): 0, (52.7% identity in 311 aa overlap). Equivalent to AL049491|MLCB1222_17 Mycobacterium leprae (312 aa) (93.6% identity in 312 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). TBparse score is 0.912. BELONGS TO THE PANTOTHENATE KINASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12206201221558-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1122c|coaA
MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
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