Gene Mb1123 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglyA1
Gene length1281 bp
IdentifierMb1123
Location 1221946 bp
Protein summary information
Molecular mass45001.3 Da
Isoelectric point6.5802
Protein length426 amino acids
Orthologs
M. tuberculosis H37RvRv1093
M. tuberculosis MTBC0mtbc0_001176
Cross-references
UniProtP59953
UniProtKB/TrEMBLX2BH08, P59953
General annotation
TypeCDS
FunctionUnknown
Productserine hydroxymethyltransferase 1 glya1
CommentsMb1123, glyA1, len: 426 aa. Equivalent to Rv1093,len: 426 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 426 aa overlap). Probable glyA1, serine hydroxymethyltransferase 1 (EC 2.1.2.1), equivalent to AL049491|MLCB1222_16 from Mycobacterium leprae (426 aa),FASTA score: (89.9 % identity in 426 aa overlap). Also similar to many e.g. P34895|GLYA_HYPME HYPHOMICROBIUM METHYLOVORUM (434 aa), FASTA scores: opt: 1492, E(): 0,(56.8% identity in 419 aa overlap); etc. BELONGS TO THE SHMT FAMILY. Note that previously known as glyA.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12219461223226+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1123|glyA1
MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFAPRAVLQAQGSVLTNKYAEGLPGRRYYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLVGR
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