Gene Mb1158c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameppdK
Gene length1473 bp
IdentifierMb1158c
Location 1251303 bp
Protein summary information
Molecular mass52072.8 Da
Isoelectric point4.6763
Protein length490 amino acids
Orthologs
M. tuberculosis H37RvRv1127c
M. tuberculosis MTBC0mtbc0_001210
Cross-references
UniProtA0A1R3XXF3
InterProIPR002192, IPR008279, IPR010121, IPR013815, IPR013816
UniProtKB/TrEMBLQ7U0L2
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PYRUVATE, PHOSPHATE DIKINASE PPDK
CommentsMb1158c, ppdK, len: 490 aa. Equivalent to Rv1127c,len: 490 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 490 aa overlap). Probable ppdK,Pyruvate, phosphate dikinase (EC 2.7.9.1). Equivalent (but shorter) to Z94723|MLCB33_16 ppdK from Mycobacterium leprae (601 aa) (71.8% identity in 478 aa overlap). Highly similar to N-terminus of PODK_CLOSY|P22983 pyruvate,phosphate dikinase from Clostridium symbiosum (873 aa),FASTA scores: opt: 786, E(): 0, (37.4% identity in 514 aa overlap).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12513031252775-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1158c|ppdK
MTRITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRRHHLPVPPAFCITTEVGVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFGRGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPGAADFAHDTRRRFTSMYRRIVGSAGPITDDPYAQLRASIEAVFASWNSPRAVAYRDHHGLDDQGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWLPGGQGDDVVSGLVAVAPITALRDQQPAVYDQLMAAARSLERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHHEGLIDDTETLRRVTPTHIETLLRPSLQPETRLAAPLLAKGLPACPGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVDGYEGEVRQGVLALSAWSESDTPELRELADIAQRISS
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