Gene Mb1217c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD21
Gene length1737 bp
IdentifierMb1217c
Location 1327026 bp
Protein summary information
Molecular mass62756.9 Da
Isoelectric point5.0573
Protein length578 amino acids
Orthologs
M. tuberculosis H37RvRv1185c
M. tuberculosis MTBC0mtbc0_001273
Cross-references
UniProtP63524
UniProtKB/TrEMBLX2BH57, P63524
General annotation
TypeCDS
FunctionUnknown
Productprobable fatty-acid-amp ligase fadd21 (fatty-acid-amp synthetase) (fatty-acid-amp synthase)
CommentsMb1217c, fadD21, len: 578 aa. Equivalent to Rv1185c, len: 578 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 578 aa overlap). Probable fadD21, fatty-acid-CoA synthetase (EC 6.2.1.-), highly similar to several from Mycobacteria e.g. NP_301895.1|NC_002677 possible acyl-CoA synthase from Mycobacterium leprae (579 aa); P71495|U75685 ACYL-COA SYNTHASE from Mycobacterium bovis (582 aa), FASTA scores: opt: 2388, E(): 0, (61.8% identity in 579 aa overlap); etc. SEEMS TO BELONG TO THE ATP-DEPENDENT AMP-BINDING ENZYME FAMILY.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13270261328762-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1217c|fadD21
MSDSSVLSLLRERAGLQPDDAAFTYIDYEQDWAGITETLTWSEVFRRTRIVAHEVRRHCTTGDRAVILAPQGLAYIAAFLGSMQAGAIAVPLSVPQIGSHDERVSAVLADASPSVILTTSAVAEAVAEHIHRPNTNNVGPIIEIDSLDLTGNSPSFRVKDLPSAAYLQYTSGSTRAPAGVMISHRNLQANFQQLMSNYFGDRNGVAPPDTTIVSWLPFYHDMGLVLGIIAPILGGYRSELTSPLAFLQRPARWLHSLANGSPSWSAAPNFAFELAVRKTTDADIEGLDLGNVLGITSGAERVHPNTLSRFCNRFAPYNFREDMIRPSYGLAEATLYVASRNSGDKPEVVYFEPDKLSTGSANRCEPKTGTPLLSYGMPTSPTVRIVDPDTCIECPAGTIGEIWVKGDNVAEGYWNKPDETRHTFGAMLVHPSAGTPDGSWLRTGDLGFLSEDEMFIVGRMKDMLIVYGRNHYPEDIESTVQEITGGRVAAISVPVDHTEKLVTVIELKLLGDSAGEAMDELDVIKNNVTAAISRSHGLNVADLVLVPPGSIPTTTSGKIRRAACVEQYRLQQFTRLDG
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