Gene Mb1246c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE14
Gene length375 bp
IdentifierMb1246c
Location 1358493 bp
Protein summary information
Molecular mass12743.4 Da
Isoelectric point9.2242
Protein length124 amino acids
Orthologs
M. tuberculosis H37RvRv1214c
Cross-references
UniProtA0A1R3XXP3
InterProIPR000084
UniProtKB/TrEMBLQ7U0D6
General annotation
TypeCDS
FunctionUnknown
Productpe family protein pe14
CommentsMb1246c, PE14, len: 124 aa. Equivalent to 5' end of Rv1214c, len: 110 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 68 aa overlap). Member of Mycobacterium tuberculosis PE family, appears to be frameshifted but sequence appears to be correct. The 5'-end is atypical as first 9 aa appear to be missing. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PE14 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 5 bp deletion (cttgt-*) leads to a diffferent COOH terminus.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13584931358867-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1246c|PE14
MLASAATDLAGIGSALSAANAAAAAPTTAMLAACADEVSAVVASLFARHAQAYQALSLQATAFHQQFVPDRRWRGLCGCRSRQRCCGAERAARRAECDQRSHPGTVRSVTAPMADRAKTAGPGG
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