Gene Mb1252c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1252c
Gene length648 bp
IdentifierMb1252c
Location 1364745 bp
Protein summary information
Molecular mass22107.1 Da
Isoelectric point4.607
Protein length215 amino acids
Orthologues
M. tuberculosisRv1220c
Cross-references
UniProtQ7U0D0
UniProtKB/TrEMBLX2BH72, Q7U0D0
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE METHYLTRANSFERASE
CommentsMb1252c, -, len: 215 aa. Equivalent to Rv1220c,len: 215 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 215 aa overlap). Possible methyltransferase (EC 2.1.1.-), some similarity to MDMC_STRMY|Q00719 o-methyltransferase from Streptomyces mycarofaciens (221 aa), FASTA scores; opt: 289, E(): 1.3e-07, (30.0% identity in 203 aa overlap). Also similar to Mycobacterium tuberculosis methyltransferases Rv0187|MTCI28.26 (32.9% identity in 222 aa overlap) and Rv1703c. Start site chosen by homology; other possible start sites exist upstream.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13647451365392-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1252c|Mb1252c
MPGQPAPSRGESLWAHAEGSISEDVILAGARERATDIGAGAVTPAVGALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTIDIEPEHLRLARQAFAEAGIGPSRTRLISGRAQEVLTRLADASYDLVFIDADPIDQPDYVAEGVRLLRSGGVIVVHRAALGGRAGDPGARDAEVIAVREAARLIAEDERLTPALVPLGDGVLAAVRD
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