Gene Mb1272 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemdh
Gene length990 bp
IdentifierMb1272
Location 1384457 bp
Protein summary information
Molecular mass34321.8 Da
Isoelectric point4.3991
Protein length329 amino acids
Orthologues
M. tuberculosisRv1240
Cross-references
UniProtP0A5J7
UniProtKB/TrEMBLX2BH84, P0A5J7
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE MALATE DEHYDROGENASE MDH
CommentsMb1272, mdh, len: 329 aa. Equivalent to Rv1240,len: 329 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 329 aa overlap). Probable mdh, Malate dehydrogenase (EC 1.1.1.37). Most similar to P50917|MDH_MYCLE MALATE DEHYDROGENASE from Mycobacterium leprae (329 aa), FASTA scores: opt: 1887, E(): 0, (89.1% identity in 329 aa overlap). Contains PS00068 Malate dehydrogenase active site signature. BELONGS TO THE LDH FAMILY. MDH SUBFAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13844571385446+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1272|mdh
MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDDCAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAVAADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIKKMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSAASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLEIDEFSRGRIDKSTAELADERSAVTELGLI
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