Gene Mb1294
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE AMIDASE AMIB2 (AMINOHYDROLASE) |
| Comments | Mb1294, amiB2, len: 462 aa. Equivalent to Rv1263,len: 462 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 462 aa overlap). Probable amiB2, amidase (EC 3.5.1.4). Similar to G1001278 hypothetical 54.3 kDa protein (506 aa), FASTA scores: opt: 767, E(): 7.6e-40,(32.8% identity in 461 aa overlap), also similar to G580673 rhodococcus enantiose lective amidase gene (462 aa), FASTA scores, opt: 668, E(): 7.4e-34, (33.5% identity in 484 aa overlap); and to NYLA_PSES8|P13398 6-aminohexanoate-cyclic-dimer hydrolase (492 aa), FASTA scores opt: 543, E(): 3.1e-26, (33.5% identity in 493 aa overlap). Also similar to MTCY274.19c (33.5% identity in 427 aa overlap). Similar to other putative amidases in M. tuberculosis e.g. Rv2363, Rv2888c, etc. Contains PS00017 ATP/GTP-binding site motif A. BELONGS TO THE AMIDASE FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1408667 | 1410055 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1294|amiB2
MDPTDLAFAGAAAQARMLADGALTAPMLLEVYLQRIERLDSHLRAYRVVQFDRARAEAEAAQQRLDAGERLPLLGVPIAIKDDVDIAGEVTTYGSAGHGPAATSDAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWCLNRTPGGSSGGSAAAVAAGLAPVALGSDGGGSIRIPCTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLLDATTTVPGPEGEFVAAAARQPGRLRIALSTRVPTPLPVRCGKQELAAVHQAGALLRDLGHDVVVRDPDYPASTYANYLPRFFRGISDDADAQAHPDRLEARTRAIARLGSFFSDRRMAALRAAEVVLSSRIQSIFDDVDVVVTPGAATGPSRIGAYQRRGAVSTLLLVVQRVPYFQVWNLTGQPAAVVPWDFDGDGLPMSVQLVGRPYDEATLLALAAQIESARPWAHRRPSVS
Bibliography
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