Gene Mb1325 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelysA
Gene length1344 bp
IdentifierMb1325
Location 1446077 bp
Protein summary information
Molecular mass47457.9 Da
Isoelectric point5.0704
Protein length447 amino acids
Orthologues
M. tuberculosisRv1293
Cross-references
UniProtP0A5M5
UniProtKB/TrEMBLX2BHB0, P0A5M5
General annotation
TypeCDS
FunctionUnknown
Productdiaminopimelate decarboxylase lysa (dap decarboxylase)
CommentsMb1325, lysA, len: 447 aa. Equivalent to Rv1293,len: 447 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 447 aa overlap). Probable lysA,diaminopimelate decarboxylase (EC 4.1.1.20) (see citation below), almost identical to DCDA_MYCTU|P31848. Contains PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site, PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. BELONGS TO FAMILY 2 OF ORNITHINE, DAP, AND ARGININE DECARBOXYLASES.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14460771447420+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1325|lysA
MNELLHLAPNVWPRNTTRDEVGVVCIAGIPLTQLAQEYGTPLFVIDEDDFRSRCRETAAAFGSGANVHYAAKAFLCSEVARWISEEGLCLDVCTGGELAVALHASFPPERITLHGNNKSVSELTAAVKAGVGHIVVDSMTEIERLDAIAGEAGIVQDVLVRLTVGVEAHTHEFISTAHEDQKFGLSVASGAAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFELAAHRVIGLLRDVVGEFGPEKTAQIATVDLGGGLGISYLPSDDPPPIAELAAKLGTIVSDESTAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVDVSATAHRRYVSVDGGMSDNIRTALYGAQYDVRLVSRVSDAPPVPARLVGKHCESGDIIVRDTWVPDDIRPGDLVAVAATGAYCYSLSSRYNMVGRPAVVAVHAGNARLVLRRETVDDLLSLEVR
Bibliography
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