Gene Mb1326 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namethrA
Gene length1326 bp
IdentifierMb1326
Location 1447424 bp
Protein summary information
Molecular mass45552.7 Da
Isoelectric point4.5009
Protein length441 amino acids
Orthologues
M. tuberculosisRv1294
Cross-references
UniProtP63630
UniProtKB/TrEMBLX2BHN7, P63630
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE HOMOSERINE DEHYDROGENASE THRA
CommentsMb1326, thrA, len: 441 aa. Equivalent to Rv1294,len: 441 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 441 aa overlap). Probable thrA (hom),homoserine dehydrogenase (EC 1.1.1.3), highly similar to DHOM_MYCLE|P46806 from Mycobacterium leprae (441 aa),FASTA scores: opt: 2437, E():0, (89.5% identity in 438 aa overlap). Contains PS00017 ATP/GTP-binding site motif A; PS01042 Homoserine dehydrogenase signature. BELONGS TO THE HOMOSERINE DEHYDROGENASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14474241448749+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1326|thrA
MPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVVQGVSSVIRLEGTGL
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