Gene Mb1332 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehemK
Gene length978 bp
IdentifierMb1332
Location 1454614 bp
Protein summary information
Molecular mass34536.5 Da
Isoelectric point6.5997
Protein length325 amino acids
Orthologs
M. tuberculosis H37RvRv1300
M. tuberculosis MTBC0mtbc0_001392
Cross-references
UniProtA0A1R3XYA7
InterProIPR002052, IPR004556, IPR019874
UniProtKB/TrEMBLQ7U086
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE HEMK PROTEIN HOMOLOG HEMK
CommentsMb1332, hemK, len: 325 aa. Equivalent to Rv1300,len: 325 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 325 aa overlap). Probable hemK protein homolog (EC 2.1.1.-), homology suggests translation may start at aa 22, highly similar to many e.g. HEMK_MYCLE|P45832 Mycobacterium leprae (288 aa), FASTA scores: opt: 936, E(): 0, (76.7% identity in 189 aa overlap). BELONGS TO THE HEMK FAMILY OF MODIFICATION METHYLASES.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14546141455591+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1332|hemK
MTSAPATMRWGNLPLAGESGTMTLRQAIDLAAALLAEAGVDSARCDAEQLAAHLAGTDRGRLPLFEPPGDEFFGRYRDIVTARARRVPLQHLIGTVSFGPVVLHVGPGVFVPRPETEAILAWATAQSLPARPLIVDACTGSGALAVALAQHRANLGLKARIIGIDDSDCALDYARRNAAGTPVELVRADVTTPCLLPELDGQVDLMVSNPPYIPDAAVLEPEVAQHDPHHALFGGPDGMTVISAVVGLAGRWLRPGGLFAVEHDDTTSSSTVDLVSSTKLFVDVQARKDLAGRPRFVTAMRWGHLPLAGENGAIDPRQRRCRAKR
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