Gene Mb1365c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepncb1
Gene length1347 bp
IdentifierMb1365c
Location 1497248 bp
Protein summary information
Molecular mass47239.7 Da
Isoelectric point9.231
Protein length448 amino acids
Orthologues
M. tuberculosisRv1330c
Cross-references
UniProtA0A1R3XY18
InterProIPR002638, IPR006405, IPR007229
UniProtKB/TrEMBLQ7U077
General annotation
TypeCDS
FunctionUnknown
Productnicotinic acid phosphoribosyltransferase pncb1
CommentsMb1365c, -, len: 448 aa. Equivalent to Rv1330c,len: 448 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 448 aa overlap). Conserved hypothetical protein, similar to others and also several nicotinate phosphoribosyltransferases e.g. O32090 YUEK PROTEIN from Bacillus subtilis (490 aa), FASTA scores: E(): 8.6e-22,(37.9% identity in 369 aa overlap). Also similar to M. tuberculosis Rv0573c|MTV039.11c (38.0% identity in 437 aa overlap). Start changed since original submission based on similarity; previous start at position 1500740 (-61 aa).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14972481498594-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1365c|pncb1
MGPPPAARRREGEPDNQDPAGLLTDKYELTMLAAALRDGSANRPTTFEVFARRLPTGRRYGVVAGTGRLLEALPQFRFDADACELLAQFLDPATVRYLREFRFRGDIDGYAEGELYFPGSPVLSVRGSFAECVLLETLVLSIFNHDTAIASAAARMVSAAGGRPLIEMGSRRTHERAAVAAARAAYIAGFAASSNLAAQRRYGVPAHGTAAHAFTMLHAQHGGPTELAERAAFRAQVEALGPGTTLLVDTYDVTTGVANAVAAAGAELGAIRIDSGELGVLARQAREQLDRLGATRTRIVVSGDLDEFSIAALRGEPVDSYGVGTSLVTGSGAPTANMVYKLVEVDGVPVQKRSSYKKSPGGRKEALRRSRATGTITEELVHPAGRPPVIVEPHRVLTLPLVRAGQPVADTSLAAARQLVASGLRSLPADGLKLAPGEPAIPTRTIPA
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