Gene Mb1375 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namerphA
Gene length780 bp
IdentifierMb1375
Location 1504790 bp
Protein summary information
Molecular mass27381.1 Da
Isoelectric point5.1501
Protein length259 amino acids
Orthologues
M. tuberculosisRv1340
Cross-references
UniProtQ7U076
UniProtKB/TrEMBLX2BHE6, Q7U076
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE RIBONUCLEASE RPHA (RNase PH) (tRNA nucleotidyltransferase)
CommentsMb1375, rphA, len: 259 aa. Equivalent to Rv1340,len: 259 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 259 aa overlap). Probable rphA,Ribonuclease ph (EC 2.7.7.56), highly similar to others e.g. RNPH_MYCLE|P37939 from Mycobacterium leprae (259 aa),FASTA scores: opt: 1524, E(): 0, (88.8% identity in 259 aa overlap). BELONGS TO THE RNASE PH FAMILY.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15047901505569+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1375|rphA
MSKREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRKATGLGWLTAEYAMLPSATHSRSDRESVRGRLSGRTQEISRLISRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAITGAYVALADAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYEEDSRAEVDMNVVATDTGTLVEIQGTGEGATFARSTLDKLLDMALGACDTLFAAQRDALALPYPGVLPQGPPPPKAFGT
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