Gene Mb1388c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1388c
Gene length786 bp
IdentifierMb1388c
Location 1517235 bp
Protein summary information
Molecular mass28253.2 Da
Isoelectric point9.6265
Protein length261 amino acids
Orthologues
M. tuberculosisRv1353c
Cross-references
UniProtP67435
UniProtKB/TrEMBLX2BI41, P67435
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
CommentsMb1388c, -, len: 261 aa. Equivalent to Rv1353c,len: 261 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 261 aa overlap). Probable transcriptional regulatory protein, similar to TER1_ECOLI|P03038 tetracycline repressor protein class A from Escherichia coli (216 aa), FASTA scores, opt: 231,E(): 1.6e-08, (31.3% identity in 211 aa overlap). Helix turn helix motif present at aa 3859 (+3.59 SD). BELONGS TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15172351518020-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1388c|Mb1388c
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKAVAR
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