Gene Mb1396c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | ppe family protein ppe19 |
| Comments | Mb1396c, PPE19, len: 396 aa. Similar to Rv1361c,len: 396 aa, from Mycobacterium tuberculosis strain H37Rv,(92.9% identity in 396 aa overlap). PPE19 (alternate gene name: mtb39b). Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, highly similar to many e.g. Rv1196|MTCI364.08|PPE18, FASTA scores: E(): 0,(84.9% identity in 397 aa overlap); MTCY274.23c (42.3% identity in 416 aa overlap); etc. Contains PS00501 Signal peptidases I serine active site. Note that expression of Rv1361c was demonstrated in lysates by immunodetection (see first citation below). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, the PPE19 gene contains nine substitutions compared to Mycobacterium tuberculosis strain H37Rv. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1530478 | 1531668 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1396c|PPE19
MVDFGALPPEINSARMYAGPGSASLVAAAQMWDSVASDLFSAASAFQSVVWGLTVGSWIGSSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATATATATLLPFEEAPEMTSAGGLLEQAAAVEEASDTAAANQLMNNVPQALQQLAQPTQGTTPSSKLGGLWKTVSPHLSPISNIVSMLNNHVSMTNSGVSMTNTLHSMLKGFAPAAAQAVETAAQNGVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGSLSVPPAWAAANQAVTPAARALPLTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG
Bibliography
No article yet recorded
