Gene Mb1415 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepyrB
Gene length960 bp
IdentifierMb1415
Location 1549911 bp
Protein summary information
Molecular mass33818.6 Da
Isoelectric point7.1488
Protein length319 amino acids
Orthologs
M. tuberculosis H37RvRv1380
M. tuberculosis MTBC0mtbc0_001481
Cross-references
UniProtP65614
UniProtKB/TrEMBLX2BHX3, P65614
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ASPARTATE CARBAMOYLTRANSFERASE PYRB (ATCase) (Aspartate transcarbamylase)
CommentsMb1415, pyrB, len: 319 aa. Equivalent to Rv1380,len: 319 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 319 aa overlap). Probable pyrB,aspartate carbamoyltransferase (EC 2.1.3.2), similar to many e.g. PYRB_BACCL|P41008 aspartate carbamoyltransferase from Bacillus caldolyticus (308 aa), FASTA scores, opt: 639, E(): 7.3e-36, (39.5% identity in 311 aa overlap). Contains PS00097 Aspartate and ornithine carbamoyltransferases signature. BELONGS TO THE ATCASES/OTCASES FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15499111550870+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1415|pyrB
MTPRHLLTAADLSRDDATAILDDADRFAQALVGRDIKKLPTLRGRTVVTMFYENSTRTRVSFEVAGKWMSADVINVSAAGSSVGKGESLRDTALTLRAAGADALIIRHPASGAAHLLAQWTGAHNDGPAVINAGDGTHEHPTQALLDALTIRQRLGGIEGRRIVIVGDILHSRVARSNVMLLDTLGAEVVLVAPPTLLPVGVTGWPATVSHDFDAELPAADAVLMLRVQAERMNGGFFPSVREYSVRYGLTERRQAMLPGHAVVLHPGPMVRGMEITSSVADSSQSAVLQQVSNGVQVRMAVLFHVLVGAQDAGKEGAA
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