Gene Mb1416 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepyrC
Gene length1293 bp
IdentifierMb1416
Location 1550867 bp
Protein summary information
Molecular mass45240.4 Da
Isoelectric point4.882
Protein length430 amino acids
Orthologues
M. tuberculosisRv1381
Cross-references
UniProtQ7U057
UniProtKB/TrEMBLX2BHQ7, Q7U057
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DIHYDROOROTASE PYRC (DHOase)
CommentsMb1416, pyrC, len: 430 aa. Equivalent to Rv1381,len: 430 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 430 aa overlap). Probable pyrC,dihydroorotase (EC 3.5.2.3), similar to many e.g. PYRC_BACCL|P46538 (40.5% identity in 395 aa overlap). Contains PS00483 Dihydroorotase signature 2. BELONGS TO THE DHOASE FAMILY. SUBFAMILY 2.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15508671552159+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1416|pyrC
MSVLIRGVRPYGEGERVDVLVDDGQIAQIGPDLAIPDTADVIDATGHVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAELTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLTVGAFAHEGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAAGTVEILKWAKDQGISITAEVTPHHLLLDDARLASYDGVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEHEKCVEFAAARPGMLGLQTALSVVVQTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLEVGEPANLTVVDPDATWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARDGKIRA
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