Gene Mb1418
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN CARA (Carbamoyl-phosphate synthetase glutamine chain) |
| Comments | Mb1418, carA, len: 376 aa. Equivalent to Rv1383,len: 376 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 376 aa overlap). Probable carA,Carbamoyl-phosphate synthase small chain (EC 6.3.5.5),similar to many e.g. CARA_ECOLI|P00907 carbamoyl-phosphate synthase small chain from Escherichia coli (382 aa), FASTA scores: opt: 796, E(): 0, (45.5% identity in 382 aa overlap). Contains PS00442 Glutamine amidotransferases class-I active site. THE GATASE DOMAIN BELONGS TO TYPE-1 GLUTAMINE AMIDOTRANSFERASES. SUBUNIT: COMPOSED OF TWO CHAINS; THE SMALL (OR GLUTAMINE) CHAIN PROMOTES THE HYDROLYSIS OF GLUTAMINE TO AMMONIA, WHICH IS USED BY THE LARGE (OR AMMONIA) CHAIN TO SYNTHESIZE CARBAMOYL PHOSPHATE. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1552650 | 1553780 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1418|carA
MSKAVLVLEDGRVFTGRPFGATGQALGEAVFSTGMSGYQETLTDPSYHRQIVVATAPQIGNTGWNGEDSESRGERIWVAGYAVRDPSPRASNWRATGTLEDELIRQRIVGIAGIDTRGVVRHLRSRGSMKAGVFSDGALAEPADLIARVRAQQSMLGADLAGEVSTAEPYVVEPDGPPGVSRFTVAALDLGIKTNTPRNFARRGIRCHVLPASTTFEQIAELNPHGVFLSNGPGDPATADHVVALTREVLGAGIPLFGICFGNQILGRALGLSTYKMVFGHRGINIPVVDHATGRVAVTAQNHGFALQGEAGQSFATPFGPAVVSHTCANDGVVEGVKLVDGRAFSVQYHPEAAAGPHDAEYLFDQFVELMAGEGR
Bibliography
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