Gene Mb1420 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepyrF
Gene length825 bp
IdentifierMb1420
Location 1557124 bp
Protein summary information
Molecular mass27377.2 Da
Isoelectric point4.7446
Protein length274 amino acids
Orthologs
M. tuberculosis H37RvRv1385
M. tuberculosis MTBC0mtbc0_001486
Cross-references
UniProtP0A5M7
UniProtKB/TrEMBLX2BHX9, P0A5M7
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE OROTIDINE 5'-PHOSPHATE DECARBOXYLASE PYRF (OMP decarboxylase) (OMPdecase)
CommentsMb1420, pyrF, len: 274 aa. Equivalent to Rv1385,len: 274 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 274 aa overlap). Probable pyrF,orotidine 5'-phosphate decarboxylase (EC 4.1.1.23),identical to DCOP_MYCBO|P42610 Mycobacterium bovis (274 aa). Contains PS00156 Orotidine 5'-phosphate decarboxylase active site. BELONGS TO THE OMP DECARBOXYLASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15571241557948+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1420|pyrF
MTGFGLRLAEAKARRGPLCLGIDPHPELLRGWDLATTADGLAAFCDICVRAFADFAVVKPQVAFFESYGAAGFAVLERTIAELRAADVLVLADAKRGDIGATMSAYATAWVGDSPLAADAVTASPYLGFGSLRPLLEVAAAHGRGVFVLAATSNPEGAAVQNAAADGRSVAQLVVDQVGAANEAAGPGPGSIGVVVGATAPQAPDLSAFTGPVLVPGVGVQGGRPEALGGLGGAASSQLLPAVAREVLRAGPGVPELRAAGERMRDAVAYLAAV
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