Gene Mb1424 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegmk
Gene length627 bp
IdentifierMb1424
Location 1561080 bp
Protein summary information
Molecular mass22095.3 Da
Isoelectric point7.5841
Protein length208 amino acids
Orthologs
M. tuberculosis H37RvRv1389
M. tuberculosis MTBC0mtbc0_001490
Cross-references
UniProtP0A5I5
UniProtKB/TrEMBLX2BHH9, P0A5I5
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GUANYLATE KINASE GMK
CommentsMb1424, gmk, len: 208 aa. Equivalent to Rv1389,len: 208 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 208 aa overlap). Probable gmk, guanylate kinase (EC 2.7.4.8), similar to e.g. KGUA_ECOLI|P24234 guanylate kinase from Escherichia coli (207 aa), FASTA scores: opt: 424, E(): 6.6e-20, (35.9% identity in 184 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00856 Guanylate kinase signature. BELONGS TO THE GUANYLATE KINASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15610801561706+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1424|gmk
MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNLHFSVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDLQARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVSLLVGTAPGSP
Bibliography
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