Gene Mb1451 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameribH
Gene length465 bp
IdentifierMb1451
Location 1587996 bp
Protein summary information
Molecular mass15901.1 Da
Isoelectric point4.8679
Protein length154 amino acids
Orthologues
M. tuberculosisRv1416
Cross-references
UniProtP66035
UniProtKB/TrEMBLX2BHU4, P66035
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE RIBOFLAVIN SYNTHASE BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase) (DMRL synthase) (Lumazine synthase)
CommentsMb1451, ribH, len: 154 aa. Equivalent to Rv1416,len: 154 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 154 aa overlap). Probable ribH,riboflavin synthase beta chain (EC 2.5.1.9), similar to many e.g. RISB_ECOLI|P25540 Escherichia coli (156 aa),FASTA scores: opt: 330, E(): 1.8e-15, (44.1% identity in 145 aa overlap). Note alternative GTG start possible overlapping the stop codon of Rv1415|MTCY21B4.33. BELONGS TO THE DMRL SYNTHASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15879961588460+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1451|ribH
MPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDDPTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATALTLRELRAHS
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