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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs28
CommentsMb1487c, PE_PGRS28, len: 795 aa. Highly similar to Rv1452c, len: 741 aa, from Mycobacterium tuberculosis strain H37Rv, (89.1% identity in 795 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, similar to Y03A_MYCTU|Q10637 hypothetical glycine-rich 49.6 kd protein (603 aa), fasta scores: opt: 2090, E(): 0, (56.3% identity in 641 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis,substitutions of 3 bp to 144 bp, 40 bp to 49 bp, 31 bp to 31 bp, 4 bp to 4 bp (gggc-ttgg), 12 bp to 12 bp, 11 bp to 11 bp, 60 bp to 63 bp, 13 bp to 13 bp and 2 bp to 2 bp (tt-cc), and a 9 bp insertion (*-cccgccggc), leads to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (795 aa versus 741 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16325881634975-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1487c|PE_PGRS28
MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQALLGRPLIGDGAAGAPGTGQAGGAGGILWGNGGAGGSGAPGQVGGAGGAAGLFGTGGAGGAGGAGAAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGGHGGVGGAAGLLGVGGHGGAGGHGAAGIAGAAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLAGAGGAGGDGGIGGTGGAGGAGFSRALIVAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGGAGGVGGDRGAGANGNQAVNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGGHGGLVGNGGAGGAGGNGANGAAGTNASDSGAVGGKGNSGGNGGQGGAGGDGGTLAGNGGAGGTGGRGADGGLGGSGAEGANATTAGERGQDGGKGGNGGVGGTGGNAVAPGANGGHGGNGGNPGFSGAGGLGGLSGDGVTRAAQGATPDFADTGGKGGNGGNGANAVAPGGTGASGGAGGNAGAGGKGGENIIGDGGGGGNGGAGGQGGDGTAGAGGDGGAGGKGGDGGDGGSDPTEGRGFGGLGGAGGAGGKGGAGTLLGLTVFGDNGGAGVLGDSTDPDGSGGAGGAGGAGGAGGDPTI
      
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