Gene Mb1488 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1488
Gene length1266 bp
IdentifierMb1488
Location 1635127 bp
Protein summary information
Molecular mass46624.1 Da
Isoelectric point6.7283
Protein length421 amino acids
Orthologs
M. tuberculosis H37RvRv1453
M. tuberculosis MTBC0mtbc0_001555
Cross-references
UniProtA0A1R3XYD2
InterProIPR025736
UniProtKB/TrEMBLQ7U019
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSCRIPTIONAL ACTIVATOR PROTEIN
CommentsMb1488, -, len: 421 aa. Equivalent to Rv1453, len: 421 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 421 aa overlap). Possible transcriptional activator, similar to Q50018 putative transcriptional activator trx from Mycobacterium leprae (517 aa), FASTA scores: opt: 1719, E(): 0, (54.0% identity in 500 aa overlap). Also highly similar to Mycobacterium tuberculosis proteins Rv2370c, Rv1194c, Rv2242, Rv1186c,and to the further upstream ORF's Rv1429|MTCY493.25c (28.1% identity in 335 aa overlap). Start changed since first submission (-11 aa).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16351271636392+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1488|Mb1488
MALRETSPRIHELIREAARIALNPTQEWLDEFDRAILAANPSIAADPALATVVKRSNRAHLIHFAAANLRNPGAPVPANLGPEPLRMARDLVRVGLDALALDIYRIGQNVAWRRWTDIAFGLTSDPDELHELLDVPFRTANEFVDTTLAGITTEMQLERDKLTRDVPAERRKIVQLLIDGAPISREHAEARLGYPLDRSHTAAVIWGDQAQGDHSHLDRVADAFGHAGGCPHPLVVVAGAATRWVWVKDAPGFDIDLIHEVLHDIPDARIAIGATAPGIEGFRRSHRDALTTARMIIRLESPHRVAFFTDVEMVALLTENAEGADDFIQRTLGNLESASPALKTTLLTFINQQCNASRAARLLFTHRNTLMNRLETAQRLLPRPLADTTIHVAVALEAQQWREKQTSDPPAKKESNGTKMR
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