Gene Mb1506 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrxB1
Gene length372 bp
IdentifierMb1506
Location 1656116 bp
Protein summary information
Molecular mass13341.0 Da
Isoelectric point4.6512
Protein length123 amino acids
Orthologs
M. tuberculosis H37RvRv1471
M. tuberculosis MTBC0mtbc0_001573
Cross-references
UniProtA0A1R3XYF1
InterProIPR005746, IPR012336, IPR013766, IPR017937
UniProtKB/TrEMBLQ7U005
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE THIOREDOXIN TRXB1
CommentsMb1506, trxB1, len: 123 aa. Equivalent to Rv1471,len: 123 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 123 aa overlap). Probable trxB1,thioredoxin (EC 1.-.-.-), similar to many bacterial thioredoxins e.g. P33636|THI2_ECOLI from Escherichia coli (139 aa), FASTA scores: opt: 290, E(): 1.8e-13, (44.3% identity in 97 aa overlap); etc. Highly similar to Rv1470|TrxA probable thioredoxin from Mycobacterium tuberculosis (124 aa), FASTA scores: opt: 402, E(): 1.2e-32, (54.4% identity in 114 aa overlap). Contains PS00194 Thioredoxin family active site. BELONGS TO THE THIOREDOXIN FAMILY. Note that previously known as trxB.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16561161656487+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1506|trxB1
MTTRDLTAAQFNETIQSSDMVLVDYWASWCGPCRAFAPTFAESSEKHPDVVHAKVDTEAERELAAAAQIRSIPTIMAFKNGKLLFNQAGALPPAALESLVQQLKAYEVEAGEATTQNGRAQQA
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