Gene Mb1530 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemutB
Gene length2253 bp
IdentifierMb1530
Location 1680751 bp
Protein summary information
Molecular mass80604.2 Da
Isoelectric point5.6867
Protein length750 amino acids
Orthologs
M. tuberculosis H37RvRv1493
M. tuberculosis MTBC0mtbc0_001597
Cross-references
UniProtP65488
UniProtKB/TrEMBLX2BID6, P65488
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE METHYLMALONYL-COA MUTASE LARGE SUBUNIT MUTB (MCM)
CommentsMb1530, mutB, len: 750 aa. Equivalent to Rv1493,len: 750 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 750 aa overlap). Probable mutB,Methylmalonyl-coa mutase large-subunit (EC 5.4.99.2),strong similarity to e.g. MUTB_STRCM|Q05065 methylmalonyl-coa mutase alpha-subunit from Streptomyces cinnamonensis (733 aa), FASTA scores: opt: 3562, E(): 0,(75.8% identity in 730 aa overlap). Contains PS00544 Methylmalonyl-CoA mutase signature. BELONGS TO THE METHYLMALONYL-COA MUTASE FAMILY.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16807511683003+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1530|mutB
MTTKTPVIGSFAGVPLHSERAAQSPTEAAVHTHVAAAAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPFVRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLATHRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGAVLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRIISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAGLNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSAKSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRARAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKYQVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAAEQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTISGVYRDEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQKVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTLVPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADAAIDLLHRLAERLGYTLD
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