Gene Mb1563 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameileS
Gene length3126 bp
IdentifierMb1563
Location 1720532 bp
Protein summary information
Molecular mass117314.0 Da
Isoelectric point4.8109
Protein length1041 amino acids
Orthologs
M. tuberculosis H37RvRv1536
M. tuberculosis MTBC0mtbc0_001643
Cross-references
UniProtQ7VEZ0
UniProtKB/TrEMBLX2BI93, Q7VEZ0
General annotation
TypeCDS
FunctionUnknown
Productisoleucyl-tRNA synthetase ileS
CommentsMb1563, ileS, len: 1041 aa. Equivalent to Rv1536,len: 1041 aa, from Mycobacterium tuberculosis strain H37Rv, (99.9% identity in 1041 aa overlap). ileS,Isoleucyl-tRNA synthetase (EC 6.1.1.5) , similar to several e.g. SYIC_YEAST P09436 isoleucyl-tRNA synthetase (1072 aa), FASTA scores: opt: 1447, E(): 0, (37.8% identity in 1072 aa overlap); contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. BELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17205321723657+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1563|ileS
MTDNAYPKLAGGAPDLPALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMGIAAFNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVGFKVVGGQPDNGLDGAYLLVWTTTPWTLPSNLAVAVSPDITYVQVQAGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPPFAYFMDWPNAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIAPVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIRHETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMPYAQVHYPFENLDWFQGHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGTWRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNWYVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLITEIIWRGLTRERSVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPKLIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGPRLGKDVQAAIKAVKAGDGVINPDGTLLAGPAVLTADEYNSRLVAADPESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKSTGLDVSDRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFADLADGVAIGDGVRVSIEKT
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