Gene Mb1574 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namednaE1
Gene length3555 bp
IdentifierMb1574
Location 1731707 bp
Protein summary information
Molecular mass129323.0 Da
Isoelectric point5.5684
Protein length1184 amino acids
Cross-references
UniProtP63978
UniProtKB/TrEMBLX2BHX1, P63978
General annotation
TypeCDS
FunctionUnknown
Productprobable dna polymerase iii (alpha chain) dnae1 (dna nucleotidyltransferase)
CommentsMb1574, dnaE1, len: 1184 aa. Equivalent to Rv1547,len: 1184 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 1184 aa overlap). Probable dnaE1,DNA polymerase III, alpha chain (EC 2.7.7.7), similar to e.g. DP3A_ECOLI|P10443 dna polymerase III, alpha chain (1160 aa), FASTA scores: opt: 1789, E(): 0, (36.5% identity in 1193 aa overlap). Also similar to M. tuberculosis, DnaE2|Rv3370c.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17317071735261+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1574|dnaE1
MSGSSAGSSFVHLHNHTEYSMLDGAAKITPMLAEVERLGMPAVGMTDHGNMFGASEFYNSATKAGIKPIIGVEAYIAPGSRFDTRRILWGDPSQKADDVSGSGSYTHLTMMAENATGLRNLFKLSSHASFEGQLSKWSRMDAELIAEHAEGIIITTGCPSGEVQTRLRLGQDREALEAAAKWREIVGPDNYFLELMDHGLTIERRVRDGLLEIGRALNIPPLATNDCHYVTRDAAHNHEALLCVQTGKTLSDPNRFKFDGDGYYLKSAAEMRQIWDDEVPGACDSTLLIAERVQSYADVWTPRDRMPVFPVPDGHDQASWLRHEVDAGLRRRFPAGPPDGYRERAAYEIDVICSKGFPSYFLIVADLISYARSAGIRVGPGRGSAAGSLVAYALGITDIDPIPHGLLFERFLNPERTSMPDIDIDFDDRRRGEMVRYAADKWGHDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPAIMAKDIPLSGITDPSHERYKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNAGVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPACEAIGLLKMDFLGLRNLTIIGDAIDNVRANRGIDLDLESVPLDDKATYELLGRGDTLGVFQLDGGPMRDLLRRMQPTGFEDVVAVIALYRPGPMGMNAHNDYADRKNNRQAIKPIHPELEEPLREILAETYGLIVYQEQIMRIAQKVASYSLARADILRKAMGKKKREVLEKEFEGFSDGMQANGFSPAAIKALWDTILPFADYAFNKSHAAGYGMVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLPPDVNESGLNFASVGQDIRYGLGAVRNVGANVVGSLLQTRNDKGKFTDFSDYLNKIDISACNKKVTESLIKAGAFDSLGHARKGLFLVHSDAVDSVLGTKKAEALGQFDLFGSNDDGTGTADPVFTIKVPDDEWEDKHKLALEREMLGLYVSGHPLNGVAHLLAAQVDTAIPAILDGDVPNDAQVRVGGILASVNRRVNKNGMPWASAQLEDLTGGIEVMFFPHTYSSYGADIVDDAVVLVNAKVAVRDDRIALIANDLTVPDFSNAEVERPLAVSLPTRQCTFDKVSALKQVLARHPGTSQVHLRLISGDRITTLALDQSLRVTPSPALMGDLKELLGPGCLGS
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