Gene Mb1580 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefrdD
Gene length378 bp
IdentifierMb1580
Location 1744571 bp
Protein summary information
Molecular mass13753.5 Da
Isoelectric point11.1571
Protein length125 amino acids
Orthologs
M. tuberculosis H37RvRv1555
M. tuberculosis MTBC0mtbc0_001662
Cross-references
UniProtP67644
UniProtKB/TrEMBLX2BII1, P67644
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE FUMARATE REDUCTASE [MEMBRANE ANCHOR SUBUNIT] FRDD (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
CommentsMb1580, frdD, len: 125 aa. Equivalent to Rv1555,len: 125 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 125 aa overlap). Probable frdD, fumarate reductase, membrane-anchor subunit (EC 1.3.99.1), similar to others e.g. P03806|FRDD_ECOLI fumarate reductase 13 kDa hydrophobic protein from Escherichia coli strain K12 (119 aa), FASTA scores: opt: 212, E(): 4.4e-08, (36.8% identity in 106 aa overlap); etc. NOTE THAT FUMARATE REDUCTASE FORMS PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN (Rv1552|frdA), AN IRON-SULFUR (Rv1553|frdB), AND TWO HYDROPHOBIC ANCHOR PROTEINS (Rv1554|frdC and Rv1555|frdD).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17445711744948+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1580|frdD
MTPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLAMVRNPITKLVVLVLVVLALFHAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGWMLLTM
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