Gene Mb1583
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL6 |
| Comments | Mb1583, mmpL6, len: 967 aa. Equivalent to 3' end of Rv1557, len: 397 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 384 aa overlap). Probable mmpL6, conserved transmembrane transport protein (see citations below). Member of RND superfamily, with strong similarity to other members of large Mycobacterial membrane protein family belonging to RND superfamily e.g. Q11171|MML2_MYCTU|MMPL2|Rv0507|MT0528|MTCY20G9.34 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN from Mycobacterium tuberculosis (968 aa), FASTA scores: opt: 4142, E(): 0, (64.4% identity in 947 aa overlap); O53735|MML4_MYCTU|MMPL4|Rv0450c|MT0466|MTV037.14c PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN from Mycobacterium tuberculosis (967 aa), FASTA scores: opt: 4035, E(): 0, (61.5% identity in 948 aa overlap); P54881|MML4_MYCLE|MMPL4|ML2378|U1740V Putative membrane protein from Mycobacterium leprae (959 aa), FASTA scores: opt: 3961, E(): 0, (60.95% identity in 945 aa overlap); etc. BELONGS TO THE MMPL FAMILY. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 2153 bp insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Belongs to the TbD1 region. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1746206 | 1749109 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1583|mmpL6
MSNHHRPRPWLPHTIRRLSLPILLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGKVFHEFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFWGDPLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTPPPAGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFTRLPYFQSLGIPASIGVMIALAAALSLAPSVLILGSRFGCFEPKRRMRTRGWRRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPANIGYMAAERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAVFHLPGIGLVQAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADLLKQAEELGKTIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANFDDFFRPIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR
Bibliography
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