Gene Mb1625 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehisD
Gene length1317 bp
IdentifierMb1625
Location 1784949 bp
Protein summary information
Molecular mass45378.3 Da
Isoelectric point4.6346
Protein length438 amino acids
Orthologues
M. tuberculosisRv1599
Cross-references
UniProtP63951
UniProtKB/TrEMBLX2BIB0, P63951
General annotation
TypeCDS
FunctionUnknown
ProductProbable histidinol dehydrogenase HisD (HDH)
CommentsMb1625, hisD, len: 438 aa. Equivalent to Rv1599,len: 438 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 438 aa overlap). Probable hisD,histidinol dehydrogenase (EC 1.1.1.23) (see citation below) O08396. Similar to many e.g. HISX_MYCSM|P28736 from Mycobacterium smegmatis (445 aa), FASTA results: opt: 2356, E(): 0, (83.1% identity in 437 aa overlap). Contains histidinol dehydrogenase signature (PS00611).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17849491786265+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1625|hisD
MLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVRPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWVPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER
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