Gene Mb1627 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehisB
Gene length633 bp
IdentifierMb1627
Location 1787401 bp
Protein summary information
Molecular mass22769.6 Da
Isoelectric point6.8512
Protein length210 amino acids
Orthologues
M. tuberculosisRv1601
Cross-references
UniProtP64369
UniProtKB/TrEMBLX2BIE6, P64369
General annotation
TypeCDS
FunctionUnknown
ProductProbable imidazole glycerol-phosphate dehydratase hisB
CommentsMb1627, hisB, len: 210 aa. Equivalent to Rv1601,len: 210 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 210 aa overlap). Probable hisB,imidazole glycerol-phosphate dehydratase (EC 4.2.1.19). Similar to many e.g. HIS7_STRCO|P16247 from Streptomyces coelicolor (197 aa),FASTA results: opt: 763, E(): 0,(57.4% identity in 202 aa overlap). BELONGS TO THE IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17874011788033+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1627|hisB
MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVSGVPSTKGAL
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