Gene Mb1628 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehisH
Gene length621 bp
IdentifierMb1628
Location 1788030 bp
Protein summary information
Molecular mass21445.5 Da
Isoelectric point5.206
Protein length206 amino acids
Orthologues
M. tuberculosisRv1602
Cross-references
UniProtP59957
UniProtKB/TrEMBLX2BHZ9, P59957
General annotation
TypeCDS
FunctionUnknown
ProductProbable amidotransferase hisH
CommentsMb1628, hisH, len: 206 aa. Equivalent to Rv1602,len: 206 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 206 aa overlap). Probable hisH,amidotransferase (EC 2.4.2.-). Similar to many e.g. HIS5_STRCO|P16249 from Streptomyces coelicolor (222 aa),FASTA results: opt: 872, E():0, (61.0% identity in 210 aa overlap). Contains glutamine amidotransferases class-I active site (PS00442). BELONGS TO THE HISH FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17880301788650+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1628|hisH
MTAKSVVVLDYGSGNLRSAQRALQRVGAEVEVTADTDAAMTADGLVVPGVGAFAACMAGLRKISGERIIAERVAAGRPVLGVCVGMQILFACGVEFGVQTPGCGHWPGAVIRLEAPVIPHMGWNVVDSAAGSALFKGLDVDARFYFVHSYAAQRWEGSPDALLTWATYRAPFLAAVEDGALAATQFHPEKSGDAGAAVLSNWVDGL
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