Gene Mb1631 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehisF
Gene length804 bp
IdentifierMb1631
Location 1790219 bp
Protein summary information
Molecular mass27237.0 Da
Isoelectric point4.4732
Protein length267 amino acids
Orthologs
M. tuberculosis H37RvRv1605
M. tuberculosis MTBC0mtbc0_001711
Cross-references
UniProtQ7VEW8
UniProtKB/TrEMBLX2BIT7, Q7VEW8
General annotation
TypeCDS
FunctionUnknown
ProductProbable cyclase hisF
CommentsMb1631, hisF, len: 267 aa. Equivalent to Rv1605,len: 267 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 267 aa overlap). Probable hisF, cyclase involved in histidine biosynthetic pathway, similar to many e.g. AF0304|AF030405_1 Corynebacterium glutamicum cyclase (257 aa), FASTA scores: opt: 1201, E(): 0, (71.9% identity in 256 aa overlap). BELONGS TO THE HISA / HISF FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17902191791022+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1631|hisF
MYADRDLPGAGGLAVRVIPCLDVDDGRVVKGVNFENLRDAGDPVELAAVYDAEGADELTFLDVTASSSGRATMLEVVRRTAEQVFIPLTVGGGVRTVADVDSLLRAGADKVAVNTAAIACLDLLADMARQFGSQCIVLSVDARTVPVGSAPTPSGWEVTTHGGRRGTGMDAVQWAARGADLGVGEILLNSMDADGTKAGFDLALLRAVRAAVTVPVIASGGAGAVEHFAPAVAAGADAVLAASVFHFRELTIGQVKAALAAEGITVR
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