Gene Mb1638 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrpB
Gene length1233 bp
IdentifierMb1638
Location 1796493 bp
Protein summary information
Molecular mass43286.7 Da
Isoelectric point5.5528
Protein length410 amino acids
Orthologues
M. tuberculosisRv1612
Cross-references
UniProtP66985
UniProtKB/TrEMBLX2BI05, P66985
General annotation
TypeCDS
FunctionUnknown
Producttryptophan synthase, beta subunit trpb
CommentsMb1638, trpB, len: 410 aa. Equivalent to Rv1612,len: 410 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 410 aa overlap). Probable trpB,tryptophan synthase beta chain (EC 4.2.1.20). Equivalent to AL049913|MLCB1610_25 from Mycobacterium leprae (340 aa) (88.5% identity in 331 aa overlap). Similar to others e.g. TRPB_CAUCR|P12290 tryptophan synthase beta chain from Caulobacter crescentus (406 aa), FASTA scores: opt: 1662,E(): 0, (60.6% identity in 404 aa overlap). BELONGS TO THE TRPB FAMILY. TETRAMER OF TWO ALPHA AND TWO BETA CHAINS.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17964931797725+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1638|trpB
MSAAIAEPTSHDPDSGGHFGGPSGWGGRYVPEALMAVIEEVTAAYQKERVSQDFLDDLDRLQANYAGRPSPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLGQALLARRMGKTRVIAETGAGQHGVATATACALLGLDCVIYMGGIDTARQALNVARMRLLGAEVVAVQTGSKTLKDAINEAFRDWVANADNTYYCFGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLPDAVVACVGGGSNAIGIFHAFLDDPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYLLQDEDGQTIESHSISAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAMDAFGLLCRMEGIIPAIESAHAVAGALKLGVELGRGAVIVVNLSGRGDKDVETAAKWFGLLGND
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