Gene Mb1643 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepykA
Gene length1419 bp
IdentifierMb1643
Location 1801555 bp
Protein summary information
Molecular mass50685.1 Da
Isoelectric point5.3718
Protein length472 amino acids
Orthologs
M. tuberculosis H37RvRv1617
M. tuberculosis MTBC0mtbc0_001724
Cross-references
UniProtA0A1R3XYV1
InterProIPR001697, IPR011037, IPR015793, IPR015794, IPR015795, IPR015806, IPR015813
UniProtKB/TrEMBLQ7VEW3
General annotation
TypeCDS
FunctionUnknown
ProductProbable pyruvate kinase pykA
CommentsMb1643, pykA, len: 472 aa. Equivalent to Rv1617,len: 472 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 472 aa overlap). Probable pykA,pyruvate kinase (EC 2.7.1.40). FASTA best: Q46078 PYRUVATE KINASE from CORYNEBACTERIUM GLUTAMICUM (475 aa), opt: 2221, E(): 0, (72.2% identity in 468 aa overlap). BELONGS TO THE PYRUVATE KINASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18015551802973+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1643|pykA
MTRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLDKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV
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