Gene Mb1655 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepolA
Gene length2715 bp
IdentifierMb1655
Location 1816031 bp
Protein summary information
Molecular mass98472.0 Da
Isoelectric point4.7864
Protein length904 amino acids
Orthologs
M. tuberculosis H37RvRv1629
M. tuberculosis MTBC0mtbc0_001737
Cross-references
UniProtP0A551
UniProtKB/TrEMBLX2BIE3, P0A551
General annotation
TypeCDS
FunctionUnknown
Productprobable dna polymerase i pola
CommentsMb1655, polA, len: 904 aa. Equivalent to Rv1629,len: 904 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 904 aa overlap). polA, DNA polymerase I (EC 2.7.7.7). Has DNA polymerase family A signature (PS00447) at C-terminal end. FASTA best: DPO1_MYCTU|Q07700 DNA polymerase I from Mycobacterium tuberculosis (904 aa). Some similarity to Rv2090|MTCY49.30 (393 aa), E(): 2.2e-18, (38.7% identity in 292 aa overlap). BELONGS TO DNA POLYMERASE TYPE-A FAMILY.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18160311818745+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1655|polA
MVTTASAPSEDRAKPTLMLLDGNSLAFRAFYALPAENFKTRGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRLQRYPEYKANRSSTPDEFAGQIDITKEVLGALGITVLSEPGFEADDLIATLATQAENEGYRVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQYPDFAALRGDPSDNLPGIPGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVGDALRANLASVVRNRELTDLVRDVPLAQTPDTLRLQPWDRDHIHRLFDDLEFRVLRDRLFDTLAAAGGPEVDEGFDVRGGALAPGTVRQWLAEHAGDGRRAGLTVVGTHLPHGGDATAMAVAAADGEGAYLDTATLTPDDDAALAAWLADPAKPKALHEAKAAVHDLAGRGWTLEGVTSDTALAAYLVRPGQRSFTLDDLSLRYLRRELRAETPQQQQLSLLDDDDTDAETIQTTILRARAVIDLADALDAELARIDSTALLGEMELPVQRVLAKMESAGIAVDLPMLTELQSQFGDQIRDAAEAAYGVIGKQINLGSPKQLQVVLFDELGMPKTKRTKTGYTTDADALQSLFDKTGHPFLQHLLAHRDVTRLKVTVDGLLQAVAADGRIHTTFNQTIAATGRLSSTEPNLQNIPIRTDAGRRIRDAFVVGDGYAELMTADYSQIEMRIMAHLSGDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKAMSYGLAYGLSAYGLSQQLKISTEEANEQMDAYFARFGGVRDYLRAVVERARKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVAMIQVDKALNEAQLASRMLLQVHDELLFEIAPGERERVEALVRDKMGGAYPLDVPLEVSVGYGRSWDAAAH
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