Gene Mb1659 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameuvrB
Gene length2097 bp
IdentifierMb1659
Location 1822441 bp
Protein summary information
Molecular mass78070.4 Da
Isoelectric point4.7938
Protein length698 amino acids
Orthologs
M. tuberculosis H37RvRv1633
M. tuberculosis MTBC0mtbc0_001741
Cross-references
UniProtP67423
UniProtKB/TrEMBLX2BIR5, P67423
General annotation
TypeCDS
FunctionUnknown
Productprobable excinuclease abc (subunit b-helicase) uvrb
CommentsMb1659, uvrB, len: 698 aa. Equivalent to Rv1633,len: 698 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 698 aa overlap). uvrB, Excinuclease abc subunit B, has ATP/GTP-binding site motif A (P-loop; PS00017) near N-terminus. FASTA best: UVRB_MICLU|P10125 from Micrococcus luteus (709 aa), opt: 3268, E(): 0,(71.3% identity in 704 aa overlap). Also similar to M. tuberculosis Rv2973c (recG); and Rv1020 (mfd). BELONGS TO THE UVRB FAMILY.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18224411824537+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1659|uvrB
MRAGGHFEVVSPHAPAGDQPAAIDELERRINAGERDVVLLGATGTGKSATTAWLIERLQRPTLVMAPNKTLAAQLANELREMLPHNAVEYFVSYYDYYQPEAYIAQTDTYIEKDSSINDDVERLRHSATSALLSRRDVVVVASVSCIYGLGTPQSYLDRSVELKVGEEVPRDGLLRLLVDVQYTRNDMSFTRGSFRVRGDTVEIIPSYEELAVRIEFFGDEIEALYYLHPLTGEVIRQVDSLRIFPATHYVAGPERMAHAVSAIEEELAERLAELESQGKLLEAQRLRMRTNYDIEMMRQVGFCSGIENYSRHIDGRGPGTPPATLLDYFPEDFLLVIDESHVTVPQIGGMYEGDISRKRNLVEYGFRLPSACDNRPLTWEEFADRIGQTVYLSATPGPYELSQTGGEFVEQVIRPTGLVDPKVVVKPTKGQIDDLIGEIRTRADADQRVLVTTLTKKMAEDLTDYLLEMGIRVRYLHSEVDTLRRVELLRQLRLGDYDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSSRSLIQTIGRAARNVSGEVHMYADKITDSMREAIDETERRRAKQIAYNEANGIDPQPLRKKIADILDQVYREADDTAVVEVGGSGRNASRGRRAQGEPGRAVSAGVFEGRDTSAMPRAELADLIKDLTAQMMAAARDLQFELAARFRDEIADLKRELRGMDAAGLK
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