Gene Mb1660 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1660
Gene length1416 bp
IdentifierMb1660
Location 1824534 bp
Protein summary information
Molecular mass47812.4 Da
Isoelectric point10.0767
Protein length471 amino acids
Orthologues
M. tuberculosisRv1634
Cross-references
UniProtA0A1R3XZR8
InterProIPR011701, IPR016196, IPR020846
UniProtKB/TrEMBLQ7VEV8
General annotation
TypeCDS
FunctionUnknown
ProductPossible drug efflux membrane protein
CommentsMb1660, -, len: 471 aa. Equivalent to Rv1634, len: 471 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 471 aa overlap). Possible drug efflux membrane protein of major facilitator superfamily (MFS),similar to many antibiotic resistance (efflux) proteins. FASTA best: Q56175 TU22 DTDP-GLUCOSE DEHYDRTATASE (GRAE) from Streptomyces violaceoruber (557 aa), opt: 415, E(): 1.7e-17, (26.7% identity in 446 aa overlap). Relatives in Mycobacterium tuberculosis: MTCY369.27c, E(): 4.8e-12; MTCY20B11.14c, E(): 2.9e-10.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18245341825949+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1660|Mb1660
MTETASETGSWRELLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGRVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQTAGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR
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