Gene Mb1721 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameppnK
Gene length924 bp
IdentifierMb1721
Location 1904088 bp
Protein summary information
Molecular mass32903.7 Da
Isoelectric point5.1009
Protein length307 amino acids
Orthologs
M. tuberculosis H37RvRv1695
M. tuberculosis MTBC0mtbc0_001803
Cross-references
UniProtP0A5S7
UniProtKB/TrEMBLX2BIZ9, P0A5S7
General annotation
TypeCDS
FunctionUnknown
Productinorganic polyphosphate/atp-nad kinase ppnk (poly(p)/atp nad kinase)
CommentsMb1721, ppnK, len: 307 aa. Equivalent to Rv1695,len: 307 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 307 aa overlap). Probable ppnK,inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23),equivalent to Q49897|MLC1351.13C|Z95117|PPNK_MYCLE INORGANIC POLYPHOSPHATE/ATP-NAD KINASE from Mycobacterium leprae (311 aa) (87.9% identity in 305 aa overlap). Also similar to many e.g. P37768|PPNK_ECOLI PROBABLE INORGANIC POLYPHOSPHATE/ATP-NAD KINASE (292 aa), FASTA scores: opt: 384, E(): 1.7e-23, (33.5% identity in 233 aa overlap); etc. BELONGS TO THE NAD KINASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19040881905011+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1721|ppnK
MTAHRSVLLVVHTGRDEATETARRVEKVLGDNKIALRVLSAEAVDRGSLHLAPDDMRAMGVEIEVVDADQHAADGCELVLVLGGDGTFLRAAELARNASIPVLGVNLGRIGFLAEAEAEAIDAVLEHVVAQDYRVEDRLTLDVVVRQGGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEATIAIEIEADGHDALVFCDGRREMLIPAGSRLEVTRCVTSVKWARLDSAPFTDRLVRKFRLPVTGWRGK
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