Gene Mb1729c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1729c
Gene length591 bp
IdentifierMb1729c
Location 1914472 bp
Protein summary information
Molecular mass21569.5 Da
Isoelectric point5.9385
Protein length196 amino acids
Orthologs
M. tuberculosis H37RvRv1703c
M. tuberculosis MTBC0mtbc0_001812
Cross-references
UniProtA0A1R3Y172
InterProIPR002935, IPR025782
UniProtKB/TrEMBLQ7VEU3
General annotation
TypeCDS
FunctionUnknown
ProductProbable catechol-o-methyltransferase
CommentsMb1729c, -, len: 196 aa. Equivalent to Rv1703c,len: 196 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 196 aa overlap). Probable catechol-o-methyltransferase (EC 2.1.1.6), most similar to COMT_HUMAN|P21964 soluble form of mammalian catechol o-methyltransferase (271 aa), FASTA scores: opt: 405, E(): 7 .8e-29, (38.9% identity in 190 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical methyltransferases Rv0187, Rv1220c.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19144721915062-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1729c|Mb1729c
MLATIDKFAYEKSMLINVGDEKGTLLDAAVRRADPALALELGTYLGYGALRIARAAPEARVYSVELAEANASNARRIWAHAGVDDRVVCVVGTIGDGGRTLDALTEHGFATGTLDFVFLDHDKKAYLPDLQSILDRGWLHPGSIVVADNVRVPGAPKYRAYMRRQQGMSWNTIEHKTHLEYQTLVPDLVLESEYLG
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